SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans

Recent evidence shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sensitive to interferons (IFNs). However, the most effective types of IFNs and the underlying antiviral effectors remain to be defined. Here, we show that zinc finger antiviral protein (ZAP), which preferentia...

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Vydáno v:mBio
Hlavní autoři: Nchioua, Rayhane, Kmiec, Dorota, Müller, Janis A., Conzelmann, Carina, Groß, Rüdiger, Swanson, Chad M., Neil, Stuart J. D., Stenger, Steffen, Sauter, Daniel, Münch, Jan, Sparrer, Konstantin M. J., Kirchhoff, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569149/
https://ncbi.nlm.nih.gov/pubmed/33067384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01930-20
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