SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans

Recent evidence shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sensitive to interferons (IFNs). However, the most effective types of IFNs and the underlying antiviral effectors remain to be defined. Here, we show that zinc finger antiviral protein (ZAP), which preferentia...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Nchioua, Rayhane, Kmiec, Dorota, Müller, Janis A., Conzelmann, Carina, Groß, Rüdiger, Swanson, Chad M., Neil, Stuart J. D., Stenger, Steffen, Sauter, Daniel, Münch, Jan, Sparrer, Konstantin M. J., Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569149/
https://ncbi.nlm.nih.gov/pubmed/33067384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01930-20
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