SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans

Recent evidence shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sensitive to interferons (IFNs). However, the most effective types of IFNs and the underlying antiviral effectors remain to be defined. Here, we show that zinc finger antiviral protein (ZAP), which preferentia...

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Publicado en:mBio
Main Authors: Nchioua, Rayhane, Kmiec, Dorota, Müller, Janis A., Conzelmann, Carina, Groß, Rüdiger, Swanson, Chad M., Neil, Stuart J. D., Stenger, Steffen, Sauter, Daniel, Münch, Jan, Sparrer, Konstantin M. J., Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569149/
https://ncbi.nlm.nih.gov/pubmed/33067384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01930-20
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