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Conformational States of the Cytoprotective Protein Bcl-xL

Bcl-xL is a major inhibitor of apoptosis, a fundamental homeostatic process of programmed cell death that is highly conserved across evolution. Because it plays prominent roles in cancer, Bcl-xL is a major target for anticancer therapy and for studies aimed at understanding its structure and activit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Ryzhov, Pavel, Tian, Ye, Yao, Yong, Bobkov, Andrey A., Im, Wonpil, Marassi, Francesca M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567986/
https://ncbi.nlm.nih.gov/pubmed/32888404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.08.014
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