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Structural basis for activation of the growth hormone-releasing hormone receptor

Growth hormone-releasing hormone (GHRH) regulates the secretion of growth hormone that virtually controls metabolism and growth of every tissue through its binding to the cognate receptor (GHRHR). Malfunction in GHRHR signaling is associated with abnormal growth, making GHRHR an attractive therapeut...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zhou, Fulai, Zhang, Huibing, Cong, Zhaotong, Zhao, Li-Hua, Zhou, Qingtong, Mao, Chunyou, Cheng, Xi, Shen, Dan-Dan, Cai, Xiaoqing, Ma, Cheng, Wang, Yuzhe, Dai, Antao, Zhou, Yan, Sun, Wen, Zhao, Fenghui, Zhao, Suwen, Jiang, Hualiang, Jiang, Yi, Yang, Dehua, Eric Xu, H., Zhang, Yan, Wang, Ming-Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567103/
https://ncbi.nlm.nih.gov/pubmed/33060564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18945-0
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