Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence

The live-attenuated oral poliovirus vaccine (OPV or Sabin vaccine) replicates in gut-associated tissues, eliciting mucosa and systemic immunity. OPV protects from disease and limits poliovirus spread. Accordingly, vaccination with OPV is the primary strategy used to end the circulation of all poliov...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Host Microbe
Prif Awduron: Yeh, Ming Te, Bujaki, Erika, Dolan, Patrick T., Smith, Matthew, Wahid, Rahnuma, Konz, John, Weiner, Amy J., Bandyopadhyay, Ananda S., Van Damme, Pierre, De Coster, Ilse, Revets, Hilde, Macadam, Andrew, Andino, Raul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566161/
https://ncbi.nlm.nih.gov/pubmed/32330425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.04.003
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