The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study

BACKGROUND: Use of oral live-attenuated polio vaccines (OPV), and injected inactivated polio vaccines (IPV) has almost achieved global eradication of wild polio viruses. To address the goals of achieving and maintaining global eradication and minimising the risk of outbreaks of vaccine-derived polio...

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Publicat a:Lancet
Autors principals: Van Damme, Pierre, De Coster, Ilse, Bandyopadhyay, Ananda S, Revets, Hilde, Withanage, Kanchanamala, De Smedt, Philippe, Suykens, Leen, Oberste, M Steven, Weldon, William C, Costa-Clemens, Sue Ann, Clemens, Ralf, Modlin, John, Weiner, Amy J, Macadam, Andrew J, Andino, Raul, Kew, Olen M, Konopka-Anstadt, Jennifer L, Burns, Cara C, Konz, John, Wahid, Rahnuma, Gast, Christopher
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626986/
https://ncbi.nlm.nih.gov/pubmed/31174831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(19)31279-6
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