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Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence
The live-attenuated oral poliovirus vaccine (OPV or Sabin vaccine) replicates in gut-associated tissues, eliciting mucosa and systemic immunity. OPV protects from disease and limits poliovirus spread. Accordingly, vaccination with OPV is the primary strategy used to end the circulation of all poliov...
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| Veröffentlicht in: | Cell Host Microbe |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566161/ https://ncbi.nlm.nih.gov/pubmed/32330425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.04.003 |
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