β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification

β-Secretase1 (BACE1) protein concentrations and rates of enzyme activity, analyzed in human bodily fluids, are promising candidate biological markers for guidance in clinical trials investigating BACE1 inhibitors to halt or delay the dysregulation of the amyloid-β pathway in Alzheimer’s disease (AD)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Alzheimers Res Ther
Egile Nagusiak: Hampel, Harald, Lista, Simone, Vanmechelen, Eugeen, Zetterberg, Henrik, Giorgi, Filippo Sean, Galgani, Alessandro, Blennow, Kaj, Caraci, Filippo, Das, Brati, Yan, Riqiang, Vergallo, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566058/
https://ncbi.nlm.nih.gov/pubmed/33066807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00686-3
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