β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification

β-Secretase1 (BACE1) protein concentrations and rates of enzyme activity, analyzed in human bodily fluids, are promising candidate biological markers for guidance in clinical trials investigating BACE1 inhibitors to halt or delay the dysregulation of the amyloid-β pathway in Alzheimer’s disease (AD)...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Hampel, Harald, Lista, Simone, Vanmechelen, Eugeen, Zetterberg, Henrik, Giorgi, Filippo Sean, Galgani, Alessandro, Blennow, Kaj, Caraci, Filippo, Das, Brati, Yan, Riqiang, Vergallo, Andrea
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566058/
https://ncbi.nlm.nih.gov/pubmed/33066807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00686-3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires