mTOR-Dependent Role of Sestrin2 in Regulating Tumor Progression of Human Endometrial Cancer

SIMPLE SUMMARY: Mammalian target of rapamycin complex 1 (mTORC1), a key controller of growth and environmental stress signaling, is frequently activated in human cancers. Sestrin2 (SESN2), a highly conserved stress-inducible protein, is one of the negative feedback mechanisms for inhibiting chronic...

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Udgivet i:Cancers (Basel)
Main Authors: Shin, Jiha, Bae, Jeongyun, Park, Sumi, Kang, Hyun-Goo, Shin, Seong Min, Won, Gunho, Kim, Jong-Seok, Cho, Ssang-Goo, Choi, Youngsok, Oh, Sang-Muk, Shin, Jongdae, Kim, Jeong Sig, Park, Hwan-Woo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565818/
https://ncbi.nlm.nih.gov/pubmed/32899752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092515
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