FGF2 Inhibits Early Pancreatic Lineage Specification during Differentiation of Human Embryonic Stem Cells

Growth factors are important regulators during organ development. For many vertebrates (but not humans) it is known how they contribute to the formation and expansion of PDX1-positive cells during pancreas organogenesis. Here, the effects of the fibroblast growth factors FGF2, FGF7, FGF10, and epide...

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Gepubliceerd in:Cells
Hoofdauteurs: Dettmer, Rabea, Cirksena, Karsten, Münchhoff, Julia, Kresse, Jasmin, Diekmann, Ulf, Niwolik, Isabell, Buettner, Falk F. R., Naujok, Ortwin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565644/
https://ncbi.nlm.nih.gov/pubmed/32825270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091927
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