Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture

In vitro differentiation of human pluripotent stem cells (hPSCs) into definitive endoderm (DE) represents a key step towards somatic cells of lung, liver and pancreas. For future clinical applications, mass production of differentiated cells at chemically defined conditions and free of xenogeneic su...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Diekmann, Ulf, Wolling, Hanna, Dettmer, Rabea, Niwolik, Isabell, Naujok, Ortwin, Buettner, Falk F. R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353891/
https://ncbi.nlm.nih.gov/pubmed/30700818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37650-z
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