Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential

For the production and bio-banking of differentiated derivatives from human pluripotent stem cells (hPSCs) in large quantities for drug screening and cellular therapies, well-defined and robust procedures for differentiation and cryopreservation are required. Definitive endoderm (DE) gives rise to r...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Sahabian, Anais, Sgodda, Malte, Naujok, Ortwin, Dettmer, Rabea, Dahlmann, Julia, Manstein, Felix, Cantz, Tobias, Zweigerdt, Robert, Martin, Ulrich, Olmer, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953099/
https://ncbi.nlm.nih.gov/pubmed/31817235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121571
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