Suspension Culture of Human Pluripotent Stem Cells in Controlled, Stirred Bioreactors

by Olmer, Ruth, Lange, Andreas, Selzer, Sebastian, Kasper, Cornelia, Haverich, Axel, Martin, Ulrich, Zweigerdt, Robert
Published 2012

Directing Cardiomyogenic Differentiation of Human Pluripotent Stem Cells by Plasmid-Based Transient Overexpression of Cardiac Transcription Factors

by Hartung, Susann, Schwanke, Kristin, Haase, Alexandra, David, Robert, Franz, Wolfgang-Michael, Martin, Ulrich, Zweigerdt, Robert
Published 2013

Modulation of cardiomyocyte activity using pulsed laser irradiated gold nanoparticles

by Gentemann, Lara, Kalies, Stefan, Coffee, Michelle, Meyer, Heiko, Ripken, Tammo, Heisterkamp, Alexander, Zweigerdt, Robert, Heinemann, Dag
Published in Biomed Opt Express (2016)

Continuous human iPSC-macrophage production by suspension culture in stirred tank bioreactors

by Ackermann, Mania, Rafiei Hashtchin, Anna, Manstein, Felix, Carvalho Oliveira, Marco, Kempf, Henning, Zweigerdt, Robert, Lachmann, Nico
Published in Nat Protoc (2022)

A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device

by Christoffersson, Jonas, Meier, Florian, Kempf, Henning, Schwanke, Kristin, Coffee, Michelle, Beilmann, Mario, Zweigerdt, Robert, Mandenius, Carl-Fredrik
Published in Bioengineering (Basel) (2018)

Femtosecond laser-based nanosurgery reveals the endogenous regeneration of single Z-discs including physiological consequences for cardiomyocytes

by Müller, Dominik, Hagenah, Dorian, Biswanath, Santoshi, Coffee, Michelle, Kampmann, Andreas, Zweigerdt, Robert, Heisterkamp, Alexander, Kalies, Stefan M. K.
Published in Sci Rep (2019)

Large-scale production of megakaryocytes in microcarrier-supported stirred suspension bioreactors

by Eicke, Dorothee, Baigger, Anja, Schulze, Kai, Latham, Sharissa L., Halloin, Caroline, Zweigerdt, Robert, Guzman, Carlos A., Blasczyk, Rainer, Figueiredo, Constança
Published in Sci Rep (2018)

Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential

by Sahabian, Anais, Sgodda, Malte, Naujok, Ortwin, Dettmer, Rabea, Dahlmann, Julia, Manstein, Felix, Cantz, Tobias, Zweigerdt, Robert, Martin, Ulrich, Olmer, Ruth
Published in Cells (2019)

Fast and Efficient Multitransgenic Modification of Human Pluripotent Stem Cells

by Schwanke, Kristin, Merkert, Sylvia, Kempf, Henning, Hartung, Susann, Jara-Avaca, Monica, Templin, Christian, Göhring, Gudrun, Haverich, Axel, Martin, Ulrich, Zweigerdt, Robert
Published 2014

Transplantation of purified iPSC-derived cardiomyocytes in myocardial infarction

by Rojas, Sebastian V., Kensah, George, Rotaermel, Alexander, Baraki, Hassina, Kutschka, Ingo, Zweigerdt, Robert, Martin, Ulrich, Haverich, Axel, Gruh, Ina, Martens, Andreas
Published in PLoS One (2017)

Prediction of Human Induced Pluripotent Stem Cell Cardiac Differentiation Outcome by Multifactorial Process Modeling

by Williams, Bianca, Löbel, Wiebke, Finklea, Ferdous, Halloin, Caroline, Ritzenhoff, Katharina, Manstein, Felix, Mohammadi, Samira, Hashemi, Mohammadjafar, Zweigerdt, Robert, Lipke, Elizabeth, Cremaschi, Selen
Published in Front Bioeng Biotechnol (2020)

Solubilization and renaturation of biologically active human bone morphogenetic protein-4 from inclusion bodies

by Gieseler, Gesa-Maria, Ekramzadeh, Kimia, Nölle, Volker, Malysheva, Svitlana, Kempf, Henning, Beutel, Sascha, Zweigerdt, Robert, Martin, Ulrich, Rinas, Ursula, Scheper, Thomas, Pepelanova, Iliyana
Published in Biotechnol Rep (Amst) (2018)

The Long Non-coding RNA Cyrano Is Dispensable for Pluripotency of Murine and Human Pluripotent Stem Cells

by Hunkler, Hannah J., Hoepfner, Jeannine, Huang, Cheng-Kai, Chatterjee, Shambhabi, Jara-Avaca, Monica, Gruh, Ina, Bolesani, Emiliano, Zweigerdt, Robert, Thum, Thomas, Bär, Christian
Published in Stem Cell Reports (2020)

Transplantation Effectiveness of Induced Pluripotent Stem Cells Is Improved by a Fibrinogen Biomatrix in an Experimental Model of Ischemic Heart Failure

by Rojas, Sebastian V., Martens, Andreas, Zweigerdt, Robert, Baraki, Hassina, Rathert, Christian, Schecker, Natalie, Rojas-Hernandez, Sara, Schwanke, Kristin, Martin, Ulrich, Haverich, Axel, Kutschka, Ingo
Published in Tissue Eng Part A (2015)

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protei...

by Iorga, Bogdan, Schwanke, Kristin, Weber, Natalie, Wendland, Meike, Greten, Stephan, Piep, Birgit, dos Remedios, Cristobal G., Martin, Ulrich, Zweigerdt, Robert, Kraft, Theresia, Brenner, Bernhard
Published in Front Physiol (2018)

Hypoxic Conditions Promote the Angiogenic Potential of Human Induced Pluripotent Stem Cell-Derived Extracellular Vesicles

by Andrade, André Cronemberger, Wolf, Martin, Binder, Heide-Marie, Gomes, Fausto Gueths, Manstein, Felix, Ebner-Peking, Patricia, Poupardin, Rodolphe, Zweigerdt, Robert, Schallmoser, Katharina, Strunk, Dirk
Published in Int J Mol Sci (2021)

Cleavage of E-Cadherin and β-Catenin by Calpain Affects Wnt Signaling and Spheroid Formation in Suspension Cultures of Human Pluripotent Stem Cells

by Konze, Sarah A., van Diepen, Laura, Schröder, Anke, Olmer, Ruth, Möller, Hanna, Pich, Andreas, Weißmann, Robert, Kuss, Andreas W., Zweigerdt, Robert, Buettner, Falk F. R.
Published 2014

Macroscopic Fluorescence Imaging: A Novel Technique to Monitor Retention and Distribution of Injected Microspheres in an Experimental Model of Ischemic Heart Failure

by Martens, Andreas, Rojas, Sebastian V., Baraki, Hassina, Rathert, Christian, Schecker, Natalie, Hernandez, Sara Rojas, Schwanke, Kristin, Zweigerdt, Robert, Martin, Ulrich, Saito, Shunsuke, Haverich, Axel, Kutschka, Ingo
Published 2014

Sensitivity of human pluripotent stem cells to insulin precipitation induced by peristaltic pump-based medium circulation: considerations on process development

by Massai, Diana, Bolesani, Emiliano, Diaz, Diana Robles, Kropp, Christina, Kempf, Henning, Halloin, Caroline, Martin, Ulrich, Braniste, Tudor, Isu, Giuseppe, Harms, Vanessa, Morbiducci, Umberto, Dräger, Gerald, Zweigerdt, Robert
Published in Sci Rep (2017)

Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single-Use Stirred Tank Bioreactors

by Kropp, Christina, Kempf, Henning, Halloin, Caroline, Robles-Diaz, Diana, Franke, Annika, Scheper, Thomas, Kinast, Katharina, Knorpp, Thomas, Joos, Thomas O., Haverich, Axel, Martin, Ulrich, Zweigerdt, Robert, Olmer, Ruth
Published in Stem Cells Transl Med (2016)