Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors

BACKGROUND: Small membrane-permeable molecules are now widely used during maintenance and differentiation of embryonic stem cells of different species. In particular the glycogen synthase kinase 3 (GSK3) is an interesting target, since its chemical inhibition activates the Wnt/beta-catenin pathway....

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Bibliografski detalji
Glavni autori: Naujok, Ortwin, Lentes, Jana, Diekmann, Ulf, Davenport, Claudia, Lenzen, Sigurd
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008422/
https://ncbi.nlm.nih.gov/pubmed/24779365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-273
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