Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

類似資料

• LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of β-catenin
  著者:: Cselenyi, Christopher S., 等
  出版事項: (2008)
• Axil, a Member of the Axin Family, Interacts with Both Glycogen Synthase Kinase 3β and β-Catenin and Inhibits Axis Formation of Xenopus Embryos
  著者:: Yamamoto, Hideki, 等
  出版事項: (1998)
• DIX Domains of Dvl and Axin Are Necessary for Protein Interactions and Their Ability To Regulate β-Catenin Stability
  著者:: Kishida, Shosei, 等
  出版事項: (1999)
• Destruction complex dynamics: Wnt/β-catenin signaling alters Axin-GSK3β interactions in vivo
  著者:: Lybrand, Daniel B., 等
  出版事項: (2019)
• GSK3β/Axin-1/β-Catenin Complex Is Involved in Semaphorin3A Signaling
  著者:: Hida, Tomonobu, 等
  出版事項: (2012)