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The Efficacy of the Novel TSPO Ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 Compared to the Classical TSPO Ligand PK 11195 to Counteract the Release of Chemokines from LPS-Stimulated BV-2 Microglial Cells

The impact of ligands of the 18 kDa translocator protein (TSPO) on the release of chemokines is not vastly investigated. In the present study, we assessed the effect of our novel TSPO ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 compared to the classical TSPO ligand PK 11195 on chemokine release in LPS-st...

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Publicat a:Biology (Basel)
Autors principals: Monga, Sheelu, Weizman, Abraham, Gavish, Moshe
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565396/
https://ncbi.nlm.nih.gov/pubmed/32938018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9090291
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