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Membrane-Mediated Ligand Unbinding of the PK-11195 Ligand from TSPO

The translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor, is of longstanding medical interest as both a biomarker for neuroinjury and a potential drug target for neuroinflammation and other disorders. Recently, it was shown that ligand residence time is a key facto...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Dixon, Tom, Uyar, Arzu, Ferguson-Miller, Shelagh, Dickson, Alex
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820730/
https://ncbi.nlm.nih.gov/pubmed/33221248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.11.015
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