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Membrane-Mediated Ligand Unbinding of the PK-11195 Ligand from TSPO
The translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor, is of longstanding medical interest as both a biomarker for neuroinjury and a potential drug target for neuroinflammation and other disorders. Recently, it was shown that ligand residence time is a key facto...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7820730/ https://ncbi.nlm.nih.gov/pubmed/33221248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.11.015 |
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