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The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS

The 18 kDa Translocator Protein (TSPO) is a marker for microglial activation as its expression is enhanced in activated microglia during neuroinflammation. TSPO ligands can attenuate neuroinflammation and neurotoxicity. In the present study, we examined the efficacy of new TSPO ligands designed by o...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Azrad, Maya, Zeineh, Nidal, Weizman, Abraham, Veenman, Leo, Gavish, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387401/
https://ncbi.nlm.nih.gov/pubmed/30704062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030594
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