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The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS

The 18 kDa Translocator Protein (TSPO) is a marker for microglial activation as its expression is enhanced in activated microglia during neuroinflammation. TSPO ligands can attenuate neuroinflammation and neurotoxicity. In the present study, we examined the efficacy of new TSPO ligands designed by o...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Azrad, Maya, Zeineh, Nidal, Weizman, Abraham, Veenman, Leo, Gavish, Moshe
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387401/
https://ncbi.nlm.nih.gov/pubmed/30704062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030594
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