Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV

Hepatitis C virus (HCV) represents a major global health challenge and an efficient vaccine is urgently needed. Many HCV vaccination strategies employ recombinant versions of the viral E2 glycoprotein. However, recombinant E2 readily forms disulfide-bonded aggregates that might not be optimally suit...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Marín, María Q., Sliepen, Kwinten, García-Arriaza, Juan, Koekkoek, Sylvie M., Pérez, Patricia, Sorzano, Carlos Óscar S., Gómez, Carmen E., Sanders, Rogier W., Esteban, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563715/
https://ncbi.nlm.nih.gov/pubmed/32764419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030440
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