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Origin of Genome Instability and Determinants of Mutational Landscape in Cancer Cells

Genome instability is a crucial and early event associated with an increased predisposition to tumor formation. In the absence of any exogenous agent, a single human cell is subjected to about 70,000 DNA lesions each day. It has now been shown that physiological cellular processes including DNA tran...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genes (Basel)
Päätekijät: Mehrotra, Sonam, Mittra, Indraneel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563369/
https://ncbi.nlm.nih.gov/pubmed/32967144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11091101
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