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The cell-of-origin dictates the genomic landscape of breast cancers

Aberrant cell proliferation induced by activated oncogenes triggers oxidative stress and uncontrolled DNA replication, promoting genomic instability. We recently reported that human mammary stem cells exhibit the unique capacity to withstand an oncogenic activation by dint of an anti-oxidant program...

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Publicat a:Mol Cell Oncol
Autors principals: Puisieux, Alain, Pommier, Roxane M., Tissier, Agnès, Morel, Anne-Pierre
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540203/
https://ncbi.nlm.nih.gov/pubmed/28868351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1338931
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