Chargement en cours...
TREX1 dictates the immune fate of irradiated cancer cells
The optimal radiation dose and fractionation to induce anti-tumor immunity remain elusive. We recently found that the exonuclease TREX1 abrogates the immunogenicity of irradiated cancer cells by degrading interferon-stimulatory cytosolic dsDNA. TREX1 upregulation by radiation dose per fraction beyon...
Enregistré dans:
| Publié dans: | Oncoimmunology |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2017
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599078/ https://ncbi.nlm.nih.gov/pubmed/28932642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1339857 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|