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Towards precision radiotherapy for use with immune checkpoint blockers

The first evidence that radiation therapy (RT) enhances the efficacy of immune checkpoint blockers (ICBs) was obtained a dozen years ago in a mouse model of metastatic carcinoma refractory to anti-CTLA-4 treatment. At the time, ICBs had just entered clinical testing, an endeavor that culminated in 2...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Vanpouille-Box, Claire, Formenti, Silvia C, Demaria, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771850/
https://ncbi.nlm.nih.gov/pubmed/28751442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0037
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