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The cell-of-origin dictates the genomic landscape of breast cancers

Aberrant cell proliferation induced by activated oncogenes triggers oxidative stress and uncontrolled DNA replication, promoting genomic instability. We recently reported that human mammary stem cells exhibit the unique capacity to withstand an oncogenic activation by dint of an anti-oxidant program...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Puisieux, Alain, Pommier, Roxane M., Tissier, Agnès, Morel, Anne-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540203/
https://ncbi.nlm.nih.gov/pubmed/28868351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1338931
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