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Statistical models for identifying frequent hitters in high throughput screening
High throughput screening (HTS) interrogates compound libraries to find those that are “active” in an assay. To better understand compound behavior in HTS, we assessed an existing binomial survivor function (BSF) model of “frequent hitters” using 872 publicly available HTS data sets. We found large...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7560657/ https://ncbi.nlm.nih.gov/pubmed/33057035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74139-0 |
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