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High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors

An increasing number of neurodegenerative diseases are being found to be associated with the abnormal accumulation of aggregated proteins in the brain. In Parkinson’s disease, this process involves the aggregation of alpha-synuclein (α-syn) into intraneuronal inclusions. Thus, compounds that inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Pujols, Jordi, Peña-Díaz, Samuel, Conde-Giménez, María, Pinheiro, Francisca, Navarro, Susanna, Sancho, Javier, Ventura, Salvador
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372494/
https://ncbi.nlm.nih.gov/pubmed/28257086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030478
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