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High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors

An increasing number of neurodegenerative diseases are being found to be associated with the abnormal accumulation of aggregated proteins in the brain. In Parkinson’s disease, this process involves the aggregation of alpha-synuclein (α-syn) into intraneuronal inclusions. Thus, compounds that inhibit...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pujols, Jordi, Peña-Díaz, Samuel, Conde-Giménez, María, Pinheiro, Francisca, Navarro, Susanna, Sancho, Javier, Ventura, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372494/
https://ncbi.nlm.nih.gov/pubmed/28257086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030478
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