Microwave-Assisted Synthesis of Potential Bioactive Benzo-, Pyrido- or Pyrazino-thieno[3,2-d]pyrimidin-4-amine Analogs of MPC-6827

Efficient microwave-assisted chemical processes were applied to the synthesis of an array of novel N-(4-methoxyphenylamino)-2-methyl benzo-, pyrido- or pyrazino-thieno[3,2-d]pyrimidin-4-amine derivatives. These heteroaromatic systems were envisioned as potent bioisosteric analogues of MPC-6827, an a...

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Bibliographic Details
Published in:Pharmaceuticals (Basel)
Main Authors: Loidreau, Yvonnick, Nourrisson, Marie-Renée, Fruit, Corinne, Corbière, Cécile, Marchand, Pascal, Besson, Thierry
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558077/
https://ncbi.nlm.nih.gov/pubmed/32825171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090202
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