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Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines
The in vitro evaluation of thieno[3,2-d]pyrimidines identified halogenated compounds 1 and 2 with antiproliferative activity against three different cancer cell lines. A structure activity relationship study indicated the necessity of the chlorine at the C4-position for biological activity. The two...
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| Pubblicato in: | Bioorg Med Chem |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565497/ https://ncbi.nlm.nih.gov/pubmed/24631358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.02.033 |
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