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Mitotic arrest of breast cancer MDA-MB-231 cells by a halogenated thieno[3,2-d]pyrimidine

Halogenated thieno[3,2-d]pyrimidines exhibit antiproliferative activity against a variety of cancer cell models, such as the mouse lymphocytic leukemia cell line L1210 in which they induce apoptosis independent of cell cycle arrest. Here we assessed these activities on MDA-MB-231 cells, a well-estab...

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Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem Lett
Hoofdauteurs: Ross, Christina R., Temburnikar, Kartik W., Wilson, Gerald M., Seley-Radtke, Katherine L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556284/
https://ncbi.nlm.nih.gov/pubmed/25791452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.02.071
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