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Exploring Kinase Inhibition Properties of 9H-pyrimido[5,4-b]- and [4,5-b]indol-4-amine Derivatives
We previously highlighted the interest in 6,5,6-fused tricyclic analogues of 4-aminoquinazolines as kinase inhibitors in the micromolar to the nanomolar range of IC(50) values. For the generation of chemical libraries, the formamide-mediated cyclization of the cyanoamidine precursors was carried out...
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| Publicado no: | Pharmaceuticals (Basel) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7281298/ https://ncbi.nlm.nih.gov/pubmed/32397570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13050089 |
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