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Covalent inhibitors: a rational approach to drug discovery

Covalent inhibitors are recognized as an important component in drug discovery and therapeutics. Since the first appearance of covalent inhibitors in the late 18th century, the field has advanced significantly and currently about 30% of the marketed drugs are covalent inhibitors. The numerous advant...

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Detalhes bibliográficos
Publicado no:RSC Med Chem
Main Authors: Sutanto, Fandi, Konstantinidou, Markella, Dömling, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557570/
https://ncbi.nlm.nih.gov/pubmed/33479682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00154f
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