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Multicomponent reaction–derived covalent inhibitor space

The area of covalent inhibitors is gaining momentum due to recently introduced clinical drugs, but libraries of these compounds are scarce. Multicomponent reaction (MCR) chemistry is well known for its easy access to a very large and diverse chemical space. Here, we show that MCRs are highly suitabl...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Adv
मुख्य लेखकों: Sutanto, Fandi, Shaabani, Shabnam, Neochoritis, Constantinos G., Zarganes-Tzitzikas, Tryfon, Patil, Pravin, Ghonchepour, Ehsan, Dömling, Alexander
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Association for the Advancement of Science 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857676/
https://ncbi.nlm.nih.gov/pubmed/33536213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd9307
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