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Multicomponent reaction–derived covalent inhibitor space
The area of covalent inhibitors is gaining momentum due to recently introduced clinical drugs, but libraries of these compounds are scarce. Multicomponent reaction (MCR) chemistry is well known for its easy access to a very large and diverse chemical space. Here, we show that MCRs are highly suitabl...
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| Publié dans: | Sci Adv |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Association for the Advancement of Science
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7857676/ https://ncbi.nlm.nih.gov/pubmed/33536213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd9307 |
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