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QSAR and molecular docking for the search of AOX inhibitors: a rational drug discovery approach

The alternative oxidase (AOX) is a monotopic diiron carboxylate protein that catalyses the oxidation of ubiquinol and the reduction of oxygen to water. Although a number of AOX inhibitors have been discovered, little is still known about the ligand–protein interaction and essential chemical characte...

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Détails bibliographiques
Publié dans:J Comput Aided Mol Des
Auteurs principaux: Rosell-Hidalgo, Alicia, Young, Luke, Moore, Anthony L., Ghafourian, Taravat
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904559/
https://ncbi.nlm.nih.gov/pubmed/33289903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-020-00360-8
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