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Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors
The X-ray structure of the catalytic domain of the EphA3 tyrosine kinase in complex with a previously reported type II inhibitor was used to design two novel quinoxaline derivatives, inspired by kinase inhibitors that have reached clinical development. These two new compounds were characterized by a...
সংরক্ষণ করুন:
| প্রকাশিত: | RSC Med Chem |
|---|---|
| প্রধান লেখক: | , , , , , , , , , , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Royal Society of Chemistry
2020
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7557569/ https://ncbi.nlm.nih.gov/pubmed/33479666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00049c |
| ট্যাগগুলো: |
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