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Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application
Heparin is a promising antimalarial drug due to its activity in inhibiting Plasmodium invasion of red blood cells and to the lack of resistance evolution by the parasite against it, but its potent anticoagulant activity is preventing the advance of heparin along the clinical pipeline. We have determ...
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| Publié dans: | Pharmaceutics |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7557421/ https://ncbi.nlm.nih.gov/pubmed/32872434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12090825 |
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