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Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application

Heparin is a promising antimalarial drug due to its activity in inhibiting Plasmodium invasion of red blood cells and to the lack of resistance evolution by the parasite against it, but its potent anticoagulant activity is preventing the advance of heparin along the clinical pipeline. We have determ...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Lantero, Elena, Aláez-Versón, Carlos Raúl, Romero, Pilar, Sierra, Teresa, Fernàndez-Busquets, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557421/
https://ncbi.nlm.nih.gov/pubmed/32872434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12090825
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