Exploratory genome-wide interaction analysis of non-steroidal anti-inflammatory drugs and predicted gene expression on colorectal cancer risk

BACKGROUND: Regular use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with lower risk of colorectal cancer (CRC). Genome-wide interaction analysis on single variants (G×E) has identified several SNPs that may interact with NSAIDs to confer CRC risk, but variations in gene expressio...

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Bibliografski detalji
Izdano u:Cancer Epidemiol Biomarkers Prev
Glavni autori: Wang, Xiaoliang, Su, Yu-Ru, Petersen, Paneen S., Bien, Stephanie, Schmit, Stephanie L, Drew, David A., Albanes, Demetrius, Berndt, Sonja I, Brenner, Hermann, Campbell, Peter T, Casey, Graham, Chang-Claude, Jenny, Gallinger, Steven J, Gruber, Stephen B, Haile, Robert W, Harrison, Tabitha A, Hoffmeister, Michael, Jacobs, Eric J, Jenkins, Mark A, Joshi, Amit D., Li, Li, Lin, Yi, Lindor, Noralane M, Marchand, Loïc Le, Martin, Vicente, Milne, Roger, Maclnnis, Robert, Moreno, Victor, Nan, Hongmei, Newcomb, Polly A, Potter, John D, Rennert, Gad, Rennert, Hedy, Slattery, Martha L, Thibodeau, Steve N, Weinstein, Stephanie J, Woods, Michael O, Chan, Andrew T, White, Emily, Hsu, Li, Peters, Ulrike
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556991/
https://ncbi.nlm.nih.gov/pubmed/32651213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-19-1018
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