Exploratory genome-wide interaction analysis of non-steroidal anti-inflammatory drugs and predicted gene expression on colorectal cancer risk

BACKGROUND: Regular use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with lower risk of colorectal cancer (CRC). Genome-wide interaction analysis on single variants (G×E) has identified several SNPs that may interact with NSAIDs to confer CRC risk, but variations in gene expressio...

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Publicat a:Cancer Epidemiol Biomarkers Prev
Autors principals: Wang, Xiaoliang, Su, Yu-Ru, Petersen, Paneen S., Bien, Stephanie, Schmit, Stephanie L, Drew, David A., Albanes, Demetrius, Berndt, Sonja I, Brenner, Hermann, Campbell, Peter T, Casey, Graham, Chang-Claude, Jenny, Gallinger, Steven J, Gruber, Stephen B, Haile, Robert W, Harrison, Tabitha A, Hoffmeister, Michael, Jacobs, Eric J, Jenkins, Mark A, Joshi, Amit D., Li, Li, Lin, Yi, Lindor, Noralane M, Marchand, Loïc Le, Martin, Vicente, Milne, Roger, Maclnnis, Robert, Moreno, Victor, Nan, Hongmei, Newcomb, Polly A, Potter, John D, Rennert, Gad, Rennert, Hedy, Slattery, Martha L, Thibodeau, Steve N, Weinstein, Stephanie J, Woods, Michael O, Chan, Andrew T, White, Emily, Hsu, Li, Peters, Ulrike
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556991/
https://ncbi.nlm.nih.gov/pubmed/32651213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-19-1018
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