Shear rate gradients promote a bi-phasic thrombus formation on weak adhesive proteins, such as fibrinogen in a von Willebrand factor-dependent manner

Blood flow profoundly varies throughout the vascular tree due to its pulsatile nature and to the complex vessel geometry. While thrombus formation has been extensively studied in vitro under constant flow, and in vivo under normal blood flow conditions, increased attention has been paid to the impac...

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Vydáno v:Haematologica
Hlavní autoři: Receveur, Nicolas, Nechipurenko, Dmitry, Knapp, Yannick, Yakusheva, Aleksandra, Maurer, Eric, Denis, Cécile V., Lanza, François, Panteleev, Mikhail, Gachet, Christian, Mangin, Pierre H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Fondazione Ferrata Storti 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556676/
https://ncbi.nlm.nih.gov/pubmed/33054087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.235754
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