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The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity
APOBEC1 (APO1), a member of AID/APOBEC nucleic acid cytosine deaminase family, can edit apolipoprotein B mRNA to regulate cholesterol metabolism. This APO1 RNA editing activity requires a cellular cofactor to achieve tight regulation. However, no cofactors are required for deamination on DNA by APO1...
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| Publicado no: | NAR Cancer |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7556403/ https://ncbi.nlm.nih.gov/pubmed/33094286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa027 |
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