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Comparison of RNA editing activity of APOBEC1-A1CF and APOBEC1-RBM47 complexes reconstituted in HEK293T cells

RNA editing is an important form of regulating gene expression and activity. APOBEC1 cytosine deaminase was initially characterized as pairing with a cofactor, A1CF, to form an active RNA editing complex that specifically targets APOB RNA in regulating lipid metabolism. Recent studies revealed that...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Wolfe, Aaron D., Arnold, Don B., Chen, Xiaojiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443457/
https://ncbi.nlm.nih.gov/pubmed/30844405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.02.025
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