Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver

Mammalian C to U RNA is mediated by APOBEC1, the catalytic deaminase, together with RNA binding cofactors (including A1CF and RBM47) whose relative physiological requirements are unresolved. Although A1CF complements APOBEC1 for in vitro RNA editing, A1cf(–/–) mice exhibited no change in apolipoprot...

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Publicado en:RNA
Autores principales: Blanc, Valerie, Xie, Yan, Kennedy, Susan, Riordan, Jesse D., Rubin, Deborah C., Madison, Blair B., Mills, Jason C., Nadeau, Joseph H., Davidson, Nicholas O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298562/
https://ncbi.nlm.nih.gov/pubmed/30309881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.068395.118
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