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APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo

Editing of the human and murine ApoB mRNA by APOBEC1, the catalytic enzyme of the protein complex that catalyzes C-to-U RNA editing, creates an internal stop codon within the APOB coding sequence, generating two protein isoforms. It has been long held that APOBEC1-mediated editing activity is depend...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Snyder, Elizabeth M., McCarty, Christopher, Mehalow, Adrienne, Svenson, Karen L., Murray, Stephen A., Korstanje, Ron, Braun, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340909/
https://ncbi.nlm.nih.gov/pubmed/28069890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.058818.116
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