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Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells

In this study, the anti-tumor activity of ilimaquinone (IQ), a sesquiterpene quinone isolated from marine sponge Halichondria sp., in oral squamous cell carcinoma (OSCC) cells, was investigated. IQ suppressed the viability of the OSCC cell lines SCC4 and SCC2095 with IC(50) values of 7.5 and 8.5 μM,...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Lin, Cheng-Wen, Bai, Li-Yuan, Su, Jui-Hsin, Chiu, Chang-Fang, Lin, Wei-Yu, Huang, Wei-Ting, Shih, Ming-Cheng, Huang, Yu-Ting, Hu, Jing-Lan, Weng, Jing-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555415/
https://ncbi.nlm.nih.gov/pubmed/32825464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8090296
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