Cucurbitane Triterpenoid from Momordica charantia Induces Apoptosis and Autophagy in Breast Cancer Cells, in Part, through Peroxisome Proliferator-Activated Receptor γ Activation

Although the antitumor activity of the crude extract of wild bitter gourd (Momordica charantia L.) has been reported, its bioactive constituents and the underlying mechanism remain undefined. Here, we report that 3β,7β-dihydroxy-25-methoxycucurbita-5,23-diene-19-al (DMC), a cucurbitane-type triterpe...

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Detalhes bibliográficos
Main Authors: Weng, Jing-Ru, Bai, Li-Yuan, Chiu, Chang-Fang, Hu, Jing-Lan, Chiu, Shih-Jiuan, Wu, Chia-Yung
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697288/
https://ncbi.nlm.nih.gov/pubmed/23843889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/935675
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