Cucurbitane Triterpenoid from Momordica charantia Induces Apoptosis and Autophagy in Breast Cancer Cells, in Part, through Peroxisome Proliferator-Activated Receptor γ Activation

Although the antitumor activity of the crude extract of wild bitter gourd (Momordica charantia L.) has been reported, its bioactive constituents and the underlying mechanism remain undefined. Here, we report that 3β,7β-dihydroxy-25-methoxycucurbita-5,23-diene-19-al (DMC), a cucurbitane-type triterpe...

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Main Authors: Weng, Jing-Ru, Bai, Li-Yuan, Chiu, Chang-Fang, Hu, Jing-Lan, Chiu, Shih-Jiuan, Wu, Chia-Yung
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi Publishing Corporation 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697288/
https://ncbi.nlm.nih.gov/pubmed/23843889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/935675
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