Divaricoside Exerts Antitumor Effects, in Part, by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells

Cardiac glycosides (CGs), prescribed to treat congestive heart failure and arrhythmias, exert potent antitumor activity. In this study, divaricoside (DIV), a CG isolated from Strophanthus divaricatus was examined for its antitumor potency in oral squamous cell carcinoma (OSCC) cells. Cell growth was...

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Publicat a:Comput Struct Biotechnol J
Autors principals: Weng, Jing-Ru, Bai, Li-Yuan, Chiu, Shih-Jiuan, Chiu, Chang-Fang, Lin, Wei-Yu, Hu, Jing-Lan, Shieh, Tzong-Ming
Format: Artigo
Idioma:Inglês
Publicat: Research Network of Computational and Structural Biotechnology 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369261/
https://ncbi.nlm.nih.gov/pubmed/30788081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.01.004
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