Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum

Neurodegeneration of the locus coeruleus (LC) in age-related neurodegenerative diseases such as Alzheimer’s disease (AD) is well-documented. However, detailed studies of LC neurodegeneration in the full spectrum of frontotemporal lobar degeneration (FTLD) proteinopathies comparing tauopathies (FTLD-...

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Pubblicato in:Acta Neuropathol
Autori principali: Ohm, Daniel T., Peterson, Claire, Lobrovich, Rebecca, Cousins, Katheryn A.Q., Gibbons, Garrett S., McMillan, Corey T., Wolk, David A., Van Deerlin, Vivianna, Elman, Lauren, Spindler, Meredith, Deik, Andres, Siderowf, Andrew, Trojanowski, John Q., Lee, Edward B., Grossman, Murray, Irwin, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554264/
https://ncbi.nlm.nih.gov/pubmed/32804255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02210-1
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